As the brain ages, the risk of developing dementia increases. This is especially true for those with epilepsy who have had it for a long time. According to recent research published in the journal Pediatrics, people with epilepsy that began in infancy seem to have brains ten years older than those without the condition.
Being Diagnosed With Epilepsy May Cause Brain Aging
According to the study’s findings, there is an elevated risk of Alzheimer’s disease in persons with epilepsy, including memory loss, difficulty thinking clearly, and scant changes in the brain.
When it comes to brain aging and memory loss, those with uncontrolled epilepsy were more visible than those with well-managed epilepsy. Even among individuals who had been seizure-free for at least 10 years, the researchers found that they still existed.
According to the study’s principal author, Bruce Hermann, an emeritus professor of neuropsychology at the University of Wisconsin, it seems that childhood-onset epilepsy may speed up the aging process, especially among people with active epilepsy into their 60s in Madison.
Researchers have suggestions on how the two states are linked, but the specific process is not yet understood. He thinks that frequent seizures may accelerate certain cognitive declines that are associated with aging in the brain.
Over the course of more than 50 years, researchers tracked down and compared Finnish youngsters with and without epilepsy. Individuals had brain scans and cognitive tests between 2012 and 2017.
At both time points, the amyloid plaques in the brains of those with epilepsy were bigger, which is a known risk factor for Alzheimer’s disease. In the experiment, no one has been diagnosed with Alzheimer’s or dementia.
People with focal epilepsy, which affects just one side of the brain, those with epilepsy that was poorly controlled, and those with the APOE 4 genetic risk marker for Alzheimer’s disease all showed more advanced signs of brain aging than the general population.
Those with epilepsy were shown to be more likely to have additional risk factors for brain aging and cognitive decline, such as high blood pressure. Hermann is certain that here is where we may find a way to avoid it in the future, attention should be paid to health and lifestyle factors such as high blood pressure if you have epilepsy, since doing so may aid in cognitive enhancement and minimize brain aging.
On Sunday, those findings were announced at the American Epilepsy Society’s annual meeting in Chicago, Illinois. Research presented at medical symposia that have not yet been published in a peer-reviewed journal should be preliminary. Professor JaideepKapur, a neurology professor at UVA Health System in Charlottesville, Virginia, gave his opinion on the study’s conclusions, which he was not a part of.
According to him, people who suffer from Alzheimer’s disease and other kinds of dementia are more likely to suffer from epileptic seizures if they are located in the area of the brain that is important for learning, memory creation, and memory storage. Those with well-controlled epilepsy, says Kapur, had less severe brain aging and cognitive abnormalities.